Liver gene therapy corrects heart symptoms in model of rare enzyme disorder

Tuesday, September 30, 2014 - 05:31 in Health & Medicine

Researchers examined systemic delivery of a vector to replace the enzyme IDUA, which is deficient in patients with a rare enzyme deficiency disorder. The works describes how an injection of a vector expressing the IDUA enzyme to the liver can prevent most of the systemic manifestations of the disease, including those found in the heart.

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