BRCA1 deficiency increases sensitivity of ovarian cancer cells to auranofin

Saturday, January 9, 2016 - 10:02 in Health & Medicine

An anti-rheumatic drug could improve the prognosis for ovarian cancer patients exhibiting a deficiency of the DNA repair protein BRCA1, a study has found. Auranofin is currently undergoing trials for repurposing to treat recurrent epithelial ovarian cancer, which makes up around 90 per cent of diagnosed ovarian cancers.

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