SOD-mimetic M40403 is protective in cell and fly models of paraquat toxicity: Implications for Parkinson disease
Wednesday, April 6, 2016 - 09:10
in Health & Medicine
Parkinson disease is a debilitating and incurable neurodegenerative disorder, affecting approximately 1-2% of people over sixty-five years old. Oxidative damage is considered to play a central role in the progression of Parkinson disease and strong evidence links chronic exposure to the pesticide paraquat with the incidence of the disease, most probably through the generation of oxidative damage.