Alzheimer fibrils at atomic resolution

Friday, August 5, 2016 - 11:21 in Biology & Nature

Elongated fibers (fibrils) of the beta-amyloid protein form the typical senile plaques present in the brains of patients with Alzheimer's disease. A research team has simultaneously succeeded in elucidating the structure of the most disease-relevant beta-amyloid peptide 1-42 fibrils at atomic resolution. This simplifies the targeted search for drugs to treat Alzheimer's dementia.

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