Mechanism that alters neural excitability offers window into neuropsychiatric disease
Wednesday, August 24, 2016 - 05:01
in Biology & Nature
Researchers show, for the first time, that the well-known mechanism of gene expression control -- dynamic changes in DNA methylation -- is also involved in changes to the excitability of neural cells. This suggests that DNA methylation changes that alter excitability may be a mechanism involved in neuropsychiatric disorders, and that the sites of such changes may offer a potential therapeutic target.