Researchers find proliferating cells in normal, diseased corneal endothelium

For the first time, researchers have identified rapidly proliferating cells (known as “neural crest-derived progenitor cells”) in the corneal endothelium of specimens from normal corneas and from corneas with Fuchs’ Endothelial Corneal Dystrophy (FECD), a condition in which the cells responsible for keeping the cornea clear die prematurely — often leading to blindness. The findings hold promise for new therapies to be developed using the proliferating cells to return normal clearing abilities to the cornea in patients with FECD.

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