Immune receptors amplify 'invader' signals by turning into mini-machines

Monday, November 21, 2016 - 19:21 in Biology & Nature

When a receptor on the surface of a T cell -- a sentry of the human immune system -- senses a single particle from a harmful intruder, it immediately kicks the cell into action, launching a larger immune response. But exactly how the signal from a single receptor, among thousands on each T cell, can be amplified to affect a whole cell has puzzled immunologists for decades.

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