Key feature for modeling how cells spread in fibrous environments

Thursday, June 15, 2017 - 12:52 in Biology & Nature

Many studies have shown that stiffness of the extracellular matrix, the fibrous network of collagen that surrounds cells, promotes cellular mobility; cells can get a better grip on stiffer surfaces and thus invade neighboring tissue. New research by scientists in the University of Pennsylvania School of Engineering and Applied Science is diving deeper into this relationship, showing that stiffness is not the only factor researchers should consider when studying this process.

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