Caspase-2 enzyme inhibitor shows promise for ameliorating fatty liver disease

Friday, September 14, 2018 - 10:52 in Health & Medicine

Researchers have discovered using mice and human clinical specimens that caspase-2, a protein-cleaving enzyme, is a critical driver of non-alcoholic steatohepatitis (NASH), a chronic and aggressive liver condition. By identifying caspase-2's critical role, they believe an inhibitor of this enzyme could provide an effective way to stop the pathogenic progression that leads to NASH -- and possibly even reverse early symptoms.

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