Two sides of a coin: Our own immune cells damage the integrity of the blood-brain barrier

Friday, February 28, 2020 - 17:00 in Biology & Nature

Researchers have shown that microglia, a class of immune cells in the brain, regulate the permeability of the brain's protective barrier in response to systemic inflammation. During inflammation, microglia initially protect the barrier's integrity, but they can later reverse their behavior and increase the barrier's permeability.

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