Transdifferentiation: Antibody Directly Transforms Bone Marrow Cells Into Brain Cells

Researchers have found a way to turn bone marrow stem cells directly into brain cells, bypassing current cumbersome techniques and bringing about the possibility of simpler and safer methods. Stem cell therapies derived from patients' own cells are widely hoped to one day treat spinal cord injuries, strokes and other conditions throughout the body, with no immune rejection. "These results highlight the potential of antibodies as versatile manipulators of cellular functions," said Richard A. Lerner of The Scripps Research Institute (TSRI, principal investigator for the new study. "This is a far cry from the way antibodies used to be thought of—as molecules that were selected simply for binding and not function." read more

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