Ovarian Cancer Cells Are More Aggressive On Soft Tissues

Saturday, May 10, 2014 - 17:50 in Biology & Nature

When ovarian cancer spreads from the ovaries it almost always does so to a layer of fatty tissue that lines the gut. A new study has found that ovarian cancer cells are more aggressive on these soft tissues due to the mechanical properties of this environment. The finding is contrary to what is seen with other malignant cancer cells that seem to prefer stiffer tissues. "What we found is that there are some cancer cells that respond to softness as opposed to stiffness," said Michelle Dawson, an assistant professor in the School of Chemical and Biomolecular Engineering at the Georgia Institute of Technology. "Ovarian cancer cells that are highly metastatic respond to soft environments by becoming more aggressive." read more

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