MDH2: Mitochondrial Enzyme Targeting May Reduce Chemotherapy Side Effects
Wednesday, December 10, 2014 - 16:20
in Health & Medicine
Two compounds appear to block the cardiac damage caused by the chemotherapy drug doxorubicin, according to a report in Science Translational Medicine which indicates that inhibiting the action of the enzyme MDH2, which is key to the generation of cellular energy in mitochondria, could prevent doxorubicin-induced damage to cardiac cells without reducing the drug's anti-tumor effects. read more