Vitamin C Stresses And Kills Mutant Cancer Cells

Colorectal cancer cells with certain mutations "handle" vitamin C differently than other cells, and this difference ultimately kills them, finds a new study. The idea that vitamin C could be an effective therapy for human cancer holds great appeal, but its track record in this arena has been more claim than data, with most clinical studies finding no evidence. Several ongoing clinical studies are exploring whether a therapeutic effect may require a high plasma level of vitamin C that can be achieved only by intravenous, not oral, administration. In the meantime, the molecular mechanism by which vitamin C might selectively kill cancer cells remains unclear. read more

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