Novel mouse model for autism yields clues to a 50-year-old mystery
Wednesday, March 21, 2012 - 12:30
in Biology & Nature
Early disruptions in serotonin signaling in the brain may contribute to autism spectrum disorder (ASD), and other "enduring effects on behavior," researchers report. The investigators previously identified genetic variations in children with ASD that disrupt the function of the serotonin transporter, which regulates the supply of serotonin. Now, they report the creation of a mouse model that expresses the most common of these variations.