Scientists identify gene that may make humans more vulnerable to pulmonary tuberculosis

Saturday, October 11, 2008 - 00:15 in Biology & Nature

Researchers from the Genome Institute of Singapore (GIS) and its collaborators have now identified for the first time a new gene that may confer susceptibility to pulmonary tuberculosis. Their findings, published October 10 in the open access journal PLoS Genetics, reported that a gene named Toll-like receptor 8 (TLR8), previously shown only to recognize some factors from viruses such as the human immunodeficiency virus (HIV), has a probable role in human susceptibility to Mycobacterium tuberculosis infections. The results from the study also found that males are more susceptible than females.

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