New label-free method tracks molecules and drugs in live cells

A new type of highly sensitive microscopy developed by Harvard researchers could greatly expand the limits of modern biomedical imaging, allowing scientists to track the location of minuscule metabolites and drugs in living cells and tissues without the use of any kind of fluorescent labeling. The technique, based on stimulated Raman scattering (SRS), works by detecting the vibrations in chemical bonds between atoms. SRS microscopy could provide scientists with a potent new form of real-time, three-dimensional bioimaging free of fluorescent labels that can hinder many biological processes. read more

Read the whole article on Harvard Science

More from Harvard Science