Colon cancer connection

Monday, October 17, 2011 - 17:00 in Health & Medicine

Scientists at Harvard-afilliated Dana-Farber Cancer Institute and the Broad Institute have found strikingly high levels of a bacterium in colorectal cancers, a sign that it might contribute to the disease and potentially be a key to diagnosing, preventing, and treating it. In a study published online in the journal Genome Research, investigators report the discovery of an abnormally large number of Fusobacterium cells in nine colorectal tumor samples.  While the spike does not necessarily mean the bacterium helps cause colorectal cancer, it offers an enticing lead for further research, the study authors say.  The journal is also publishing a paper by researchers from the BC Cancer Agency and Simon Fraser University in Canada that reports similar findings from research conducted independently of the Dana-Farber/Broad Institute collaboration. A confirmed connection between Fusobacterium and the onset of colorectal cancer would mark the first time any microorganism has been found to play a role in this type...

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