A new approach to bladder-disease treatment
A bladder disease called interstitial cystitis affects at least a half-million people in the United States, mostly women, with perhaps an equal number undiagnosed. At present, there are no good options for such people; the only treatment that reduces the symptoms of painful and very frequent urination, which can be debilitating and make it impossible to work, is an infusion of the drug lidocaine into the bladder through a catheter, but the treatment only provides brief relief and needs to be repeated frequently.Researchers at MIT think they have found a much better solution. They fill a small medical-grade silicone tube with the solid drug, after drilling a tiny hole in the tube using a laser beam. A shape-memory wire made of nitinol is threaded through the tube, which is then straightened out, placed in a catheter, and inserted into the bladder. As soon as it is released there, the nitinol...