Seeing the light
There are more than 1 million blind people in the U.S., and about 100,000 of those lost their sight due to retinitis pigmentosa, a disease that destroys light-sensitive cells in the retina. There is currently no cure for retinitis pigmentosa, but scientists are working on ways to restore vision by making other cells of the retina, which are spared by the disease, sensitive to light. In a new study of mice, researchers at the University of Southern California (USC) used technology developed by a consortium of institutions, including MIT, to do just that. By inducing light sensitivity in other cells of the retina, they brought back enough vision for the mice to navigate a maze.Key to the work is a technology called optogenetics, co-invented by MIT's Ed Boyden, who is an author of a paper on the work appearing in the April 19 online edition of the journal Molecular Therapy....