MicroRNA Mediates Gene-Diet Interaction Related to Obesity

Tufts University researchers observed that a genetic variant on the perilipin 4 (PLIN4) locus was associated with an increased risk of obesity yet, carriers with higher omega-3 fatty acid intakes tended to weigh less than carriers who consumed little or no omega-3 fatty acids. Furthermore, the researchers identified a microRNA (miRNA) which may help elucidate the mechanism behind the gene-diet interaction.

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