Heat Shock Regulator Controlled by on/Off Switch and Phosphorylation
Monday, November 14, 2016 - 01:41
in Health & Medicine
Whitehead Institute researchers have determined how the master transcriptional regulator of the heat shock response, known as heat shock factor 1 (HSF1), is controlled in yeast. Understanding how HSF1 works, how it is regulated, and how to fine tune it in a cell-type specific way could lead to therapies for cancer and neurodegenerative diseases.