Tick-borne encephalitis virus reveals its access code

Fritz et al. have identified an amino acid switch that flaviviruses flip to gain access to cells. Flaviviruses such as tick-borne encephalitis virus (TBEV), yellow fever, and dengue are dangerous human pathogens. These membrane-encircled viruses enter cells by being gobbled up into endosomes and fusing their membrane with that of the endosome.

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