Enzyme with a Sugar Antenna: Researchers achieve semisynthesis of homogeneous glycoproteins

(PhysOrg.com) -- More than half of all human proteins, as well as many important pharmaceutical agents, are glycoproteins, which means that they contain sugar components. In general, natural glycoproteins do not have a homogeneous sugar component. With modern purification techniques, it is practically impossible to isolate sufficient quantities of homogeneous glycoproteins for systematic biomedical studies.

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