Camouflaging of viral DNA could be crucial step in progression of cancers

Monday, February 9, 2009 - 18:07 in Biology & Nature

An estimated 15% of cancer cases can be linked to a viral infection, however the biological changes that cause some asymptomatic carriers of a virus to develop full-blown tumors are not well understood. In a study published online in Genome Research, scientists have mapped a chemical modification of DNA in three oncogenic viruses (Epstein-Barr, human papilloma virus, and hepatitis B virus) and found that the viral genome undergoes critical changes during the progression of disease, with implications for the development of new methods of prevention, diagnosis, and treatment.

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