Upside-down world: DNA protecting protein helps cancer drug to kill cells
Tuesday, April 28, 2009 - 08:49
in Biology & Nature
Some DNA repair enzymes can become double-edged swords - If they work too slowly, they can block necessary cell maintenance and contribute to cell death. This could explain the somewhat mysterious success of the widely used cancer drug 5-Fluorouracil (5FU) and help clinicians to predict patient's response to chemotherapy, according to new findings from the University of Basel, Switzerland.