'Misreading' of histone code linked to human cancer

Monday, June 1, 2009 - 14:35 in Health & Medicine

(PhysOrg.com) -- The development of blood from stem cell to fully formed blood cell follows a genetically determined program. When it works properly, blood formation stops when it reaches maturity. But when it doesn`t, genetic mutations can prevent the stop signal and cause the developing cells to turn cancerous. In research published in Nature, Rockefeller University scientists show for the first time that a misreading of the blood cells` histone code is responsible for acute myeloid leukemia, a rare form of the deadly blood cancer.

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