Mirror images united: Simultaneous binding of both enantiomers of a drug to an enzyme
Thursday, October 29, 2009 - 06:49
in Biology & Nature
(PhysOrg.com) -- In the binding pockets of enzymes their natural binding partners fit exactly. The principle by which many pharmacological agents work also relies on the fact that these substances fit exactly into the pockets of specific enzymes. Not only the chemical properties but also the shape of the pocket determines if a molecule fits or not.