Chemists Discover How Cells Create Stability During Critical DNA-to-RNA Information Transfers

Tuesday, December 29, 2009 - 16:21 in Biology & Nature

(PhysOrg.com) -- A pair of University of Massachusetts Amherst chemists believe they have for the first time explained how the main players in transcription -- RNA polymerase, RNA (red in illustration) and the DNA template (blue) -- come together and link tightly enough to create a stable complex while DNA unwinds to pass crucial genetic information to RNA, but not so tightly that they can't come apart easily once transcription is complete. This transcription process takes place in all cells and is essential for making the proteins that carry out almost every process important to life.

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