A biotherapy strategy for esophageal cancer in the future

A research team from China focused on esophageal squamous cell carcinoma (ESCC) and characterized sphingosine 1-phosphate (S1P) receptor expression pattern and investigated the role of S1P receptors on ESCC cells proliferation and migration. Their results showed that ESCC cells may down-regulate the expression of S1P5 to promote proliferation and escape S1P-S1P5 induced migration inhibition.

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