Cell study finds receptor can fight tamoxifen-resistant breast cancer cells
Tuesday, April 27, 2010 - 18:20
in Health & Medicine
A receptor that is present in the nucleus of cells can, when activated, slow the growth of tamoxifen-resistant breast cancer cells, a new study found. The study built on the recent discovery that farnesoid X receptor (FXR) - a nuclear receptor found mainly in the liver - is found in breast cancer tissue. Although previous research showed that FXR can slow proliferation of breast cancer cells, it was not known whether it could do the same with tamoxifen-resistant cells.