Researchers discover gene network associated with vitamin A deficiency and lung birth defects

Researchers from Boston University School of Medicine (BUSM) have discovered the mechanism responsible for the failure of the lungs to form as a result of vitamin A/retinoic acid (RA) deficiency. The study, which appears in the June issue of the Journal of Clinical Investigation, also shows that corrections to this network make it possible to prevent the lung defect in retinoic acid-deficient animals.

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