Bacteriolytic therapy may be a promising treatment strategy for advanced pancreatic cancer patients

Pancreatic carcinoma is only rarely curable. A German research group investigated an alternative treatment using spores of the bacterium Clostridium novyi in an animal model. Tumors of a defined medium size were successfully treated. Small tumors remained unaffected and the treatment was toxic for animals with very large tumors. Successful treatment was due to the induction of an immune response predominantly the innate arm of the immune system.

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