Using the structure of the epidermal growth factor receptor to fight cancer
Monday, September 13, 2010 - 16:42
in Biology & Nature
(PhysOrg.com) -- The protein EGFR, which is the target of several cancer drugs, has a split personality at the cell surface, with two different classes (high-affinity and low-affinity), whose origins have been a mystery since the 1970s. Now, a new paper by Penn researchers published in Cell explains the difference between these two classes.