The Medical Minute: Doctor, why are my fingers curling up?

Dupuytren's (pronounced DOO-pwee-trens) disease or contracture is an abnormal, progressive thickening of the fascia of the hand (the layer underneath the skin). The disease is inherited, and a patient’s children have at least a 50 percent chance of carrying the abnormal gene. The severity of the disease, however, may vary greatly (new patients are often unaware of any family members having the disease). It is much more common in people of Scandinavian, British or eastern European descent.

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