Genetic risk factors identified for coronary artery disease, heart attack

Coronary artery disease (CAD) is the single largest cause of death in adults in the United States. Until recently, the genetic basis of CAD has been largely unknown, with just a few proven genes (typically genes for cholesterol disorders) accounting for very little of the disease in the population. Now, a new study from researchers at the University of Pennsylvania School of Medicine shows that certain genetic profiles increase risk of coronary artery disease (CAD) while others uniquely increase risk of heart attacks in those with CAD.

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