Basic peptides take a different route to the same destination

Thursday, January 27, 2011 - 11:52 in Biology & Nature

Flouting expectations is what a small, slightly basic protein does when it comes to breaking up, according to scientists at Pacific Northwest National Laboratory and the University of Hong Kong. Using a specialized mass spectrometer and a technique that involves propelling proteins into a hard surface, the scientists found that a certain small protein or peptide ignores the conventional approach to fragmentation, and takes a completely different path.

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