Immune cells get switched off by the gradual accumulation of dense clusters of inhibitory proteins

Friday, February 4, 2011 - 10:30 in Biology & Nature

Foreign entities within the body get chopped into pieces by antigen-presenting cells (APCs), which display the resulting chunks on their surface. These antigens can subsequently be recognized and bound by T cell receptors (TCRs), and the interaction between a T cell and an antigen-bearing APC eventually triggers the onset of an immune response against the antigen.

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