Tet further revealed: Studies track protein relevant to stem cells, cancer

Wednesday, March 30, 2011 - 12:30 in Biology & Nature

Last year, a research team at the University of North Carolina at Chapel Hill discovered one way the protein Tet 1 helps stem cells keep their pluripotency—the unique ability to become any cell type in the body. In two new studies, the team takes a broad look at the protein's location in the mouse genome, revealing a surprising dual function and offering the first genome-wide location of the protein and its product, 5-hydroxymethylcytosine—dubbed the "sixth base" of DNA.

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