Tet further revealed: Studies track protein relevant to stem cells, cancer
Wednesday, March 30, 2011 - 12:30
in Biology & Nature
Last year, a research team at the University of North Carolina at Chapel Hill discovered one way the protein Tet 1 helps stem cells keep their pluripotencythe unique ability to become any cell type in the body. In two new studies, the team takes a broad look at the protein's location in the mouse genome, revealing a surprising dual function and offering the first genome-wide location of the protein and its product, 5-hydroxymethylcytosinedubbed the "sixth base" of DNA.