8 hours of resistance: Why do cancer cells easily give in to the temptation to divide?

Wednesday, May 25, 2011 - 09:30 in Biology & Nature

Temptations to exceed the speed limit are always plentiful, but only reckless drivers give in to such impulses. Likewise, numerous growth factors always abound in our bodies, but only cancerous cells are quickly "tempted" by these chemicals to divide again and again. Healthy cells, in contrast, divide only after being exposed to growth factors for eight continuous hours. What happens during these eight hours in a healthy cell that resists the call to divide? And even more important, what fails to work properly in the cancerous cell during these same hours? Why do cancerous cells give in so easily to the influence of growth factors, dividing so readily?

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