Cholesterol boosts antibiotic resistance in H. pylori

Friday, June 17, 2011 - 07:31 in Health & Medicine

(PhysOrg.com) -- New research suggests that cholesterol boosts resistance in Helicobacter pylori both to many antibiotics and to the endogenous antimicrobial peptide, LL-37. A complete understanding of the pathway of cholesterol uptake might lead to novel strategies thwarting H. pylori by blocking that pathway, says corresponding author David McGee of Louisiana State University. The research is published in the June 2011 issue of the journal Antimicrobial Agents and Chemotherapy.

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