New breast cancer model of mutant PI3K recapitulates features of human breast cancer

Scientists from the Friedrich Miescher Institute for Biomedical Research have shown that a mutation in the lipid kinase PI3K, which occurs in about 30% of human breast cancers, itself evokes different forms of breast cancer. While this kinase has long been associated with cancer, and is a target for anti-tumor therapy, it is now shown to be causal for multiple types of breast cancer.

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