Realistic simulation of ion flux through membrane sheds light on antibiotic resistance
Tuesday, August 16, 2011 - 12:00
in Biology & Nature
As the gatekeepers of ion flow through cell membranes, ion channels are of key interest in numerous cellular processes. Now, a new study describes an innovative new computational model that realistically simulates the complex conditions found in biological systems and allows for a more accurate look at ion channel function at the level of individual atoms. The research, published by Cell Press in the August 17th issue of the Biophysical Journal, provides a remarkably detailed look at the function of a bacterial channel that kills brain cells in people with bacterial meningitis and provides insight into mechanisms that underlie deadly antibiotic resistance.