Protein involved in disease progression reveals insights for intervention

Wednesday, September 7, 2011 - 10:00 in Health & Medicine

A team of scientists from the University of Colorado and EMSL has characterized the biology of CD147, a type I transmembrane protein involved in the progression of inflammatory diseases, infections, and cancer—especially the cancer that develops in the cells of the retina, retinoblastoma. Using several methods including EMSL’s high-field nuclear magnetic resonance (NMR), the researchers also identified how the protein’s activity can be disrupted to reveal targets for therapeutic intervention.

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