'Synthetic' chromosome permits repid, on-demand 'evolution' of yeast

Wednesday, September 14, 2011 - 12:31 in Biology & Nature

In the quest to understand genomes -- how they're built, how they're organized and what makes them work -- a team of Johns Hopkins researchers has engineered from scratch a computer-designed yeast chromosome and incorporated into their creation a new system that lets scientists intentionally rearrange the yeast's genetic material. A report of their work appears September 14 as an Advance Online Publication in the journal Nature.

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