New insight into immune tolerance furthers understanding of autoimmune disease

It is no easy task to preserve the delicate balance that allows us to maintain a strong immune system that can defend us from harmful pathogens, but that is sensitive enough to correctly identify and spare our own cells. Therefore, it is not surprising that the mechanisms that underlie immune activation and tolerance are not completely understood. Now, a new research study published by Cell Press in the journal Immunity and available online on September 15th provides intriguing insight into the complex immune regulatory mechanisms that underlie immune tolerance.

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