Observed 'live': Water is an active team player for enzymes
Monday, September 19, 2011 - 09:31
in Biology & Nature
In biologically active enzyme substrate compounds, as can be found in medicines, water plays a more decisive role than has been imagined up to now. The surrounding water acts like an "adhesive", in order to keep the substrate at the right place on an enzyme. For this, the dynamism of the water is retarded. Scientists at the RUB under Prof. Dr. Martina Havenith (Physical Chemistry) in close cooperation with the group of Prof. Irit Sagi from the Israeli Weizmann Institute have been able to observe and prove the retardation of the water's dynamism "live" for the first time in close. The researchers are reporting on their results in Nature Structural & Molecular Biology.