Specialized motor proteins help control immune activation

Friday, October 7, 2011 - 09:30 in Health & Medicine

Specialized immune cells called T cells can recognize threats and induce immune responses through T cell receptors (TCRs), but these receptors do not act alone. Multiple receptors gather together at the cell surface to cooperatively switch on T cells. “The minimum unit for triggering T lymphocyte activation is known as the TCR microcluster [TCR-MC],” explains Takashi Saito of the RIKEN Research Center for Allergy and Immunology in Yokohama. “These are the key structure for T cells to recognize antigens and become activated.”

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