How major signaling pathways are wired to our genome gives new insight into disease processes
Thursday, October 27, 2011 - 12:00
in Biology & Nature
Whitehead Institute scientists have determined that master transcription factors determine the genes regulated by key signaling pathways. In this way, signaling pathways are targeted to genes that are most relevant to each cell type and tailor gene expression to control cell state, growth, differentiation, and death.