'If Hamlet give the first or second hit': The development of Burkitt's lymphoma

The human c-myc gene encodes a transcription factor (MYC) involved in the regulation of a vast number of other genes – it has been estimated that the transcription of about one in six genes is somehow under the control of MYC. Perhaps because of MYC's wide range of targets, mutations of the c-myc gene are frequently associated with a variety of tumours, not only with Burkitt's lymphoma. Mutations that lead to excessive amounts of the MYC protein are particularly threatening.

Read the whole article on Physorg

More from Physorg